Again about the "Bottom-up biology", published on the last issue of Nature.
Originally shared by Manuela Casasoli
Again about the "Bottom-up biology", published on the last issue of Nature.
Researchers are tearing up the biology rule books by trying to construct cells from scratch. A special issue explores the lessons being learnt about life.
Cells are often called the building blocks of life — but that metaphor fails to capture their complexity. How do the multitudes of different molecules within a lipid envelope come together to carry out the functions required to sustain organisms? The standard approach in biology has been to work from the top down to study how cell components interact in their natural environment. But technical advances now allow researchers to take a different tack: using engineering principles to reconstruct biological processes from the bottom up. This special issue explores the potential and possible limits of bottom-up cell biology.
Latorre et al. (2018) Active superelasticity in three-dimensional epithelia of controlled shape: https://www.nature.com/articles/s41586-018-0671-4
Fletcher (2018) Which biological systems should be engineered?: https://www.nature.com/articles/d41586-018-07291-3
Nature Editorial (2018) Focus on the benefits of building life’s systems from scratch: https://www.nature.com/articles/d41586-018-07285-1
https://www.nature.com/articles/d41586-018-07290-4
Again about the "Bottom-up biology", published on the last issue of Nature.
Researchers are tearing up the biology rule books by trying to construct cells from scratch. A special issue explores the lessons being learnt about life.
Cells are often called the building blocks of life — but that metaphor fails to capture their complexity. How do the multitudes of different molecules within a lipid envelope come together to carry out the functions required to sustain organisms? The standard approach in biology has been to work from the top down to study how cell components interact in their natural environment. But technical advances now allow researchers to take a different tack: using engineering principles to reconstruct biological processes from the bottom up. This special issue explores the potential and possible limits of bottom-up cell biology.
Latorre et al. (2018) Active superelasticity in three-dimensional epithelia of controlled shape: https://www.nature.com/articles/s41586-018-0671-4
Fletcher (2018) Which biological systems should be engineered?: https://www.nature.com/articles/d41586-018-07291-3
Nature Editorial (2018) Focus on the benefits of building life’s systems from scratch: https://www.nature.com/articles/d41586-018-07285-1
https://www.nature.com/articles/d41586-018-07290-4
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