Anti-stress compound reduces obesity and diabetes

Originally shared by Rob Jongschaap

Anti-stress compound reduces obesity and diabetes

'... For some time, researchers have known that the protein FKBP51 is associated with depression and anxiety disorders. It is involved in the regulation of the stress system – when the system does not function properly; mental disorders may develop. Now, researchers at the Max Planck Institute of Psychiatry have discovered a new, surprising role for this protein: It acts as a molecular link between the stress regulatory system and metabolic processes in the body. ...
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The protein FKBP51 can be pharmacologically blocked by antagonist compounds that were developed at the Max Planck Institute by Felix Hausch (presently at University of Darmstadt). In collaboration with the scientists at the Technical University Darmstadt and funded by the Bavarian State Ministry of Economic Affairs and Media, Energy and Technology, these compounds will be further developed for use in clinical trials. "These findings may provide a completely new treatment approach for diabetes and other metabolic diseases," states Alon Chen, Director at the Max Planck Institute of Psychiatry.
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https://medicalxpress.com/news/2017-12-anti-stress-compound-obesity-diabetes.html
https://medicalxpress.com/news/2017-12-anti-stress-compound-obesity-diabetes.html