Boosting natural brain opioids may be a better way to treat anxiety
Originally shared by Ward Plunet
Boosting natural brain opioids may be a better way to treat anxiety
Published in Nature Communications by University of Sydney scholars, the findings suggest medications that boost the effect of natural brain opioids might be a better way to reduce anxiety than 'receptor-binding' opioid drugs like morphine, which have major side effects. Fear and anxiety help defend us against harm, and are largely controlled via neural circuits of interconnected nerve cells and synaptic activity in the brain's amygdala that allow neurons to pass electrical or chemical signals to each other. Specialised neural circuits control these emotions, but disturbances in the circuits can cause prolonged and disabling emotional responses that are out of proportion to threatening events..."Our findings show that opioids produced and released by our own brain cells strongly regulate these critical neural circuits that are important for fear responses. "We also show that we could boost the actions of these endogenous opioids using a novel pharmacological approach."
https://medicalxpress.com/news/2017-03-boosting-natural-brain-opioids-anxiety.html#jCp
Boosting natural brain opioids may be a better way to treat anxiety
Published in Nature Communications by University of Sydney scholars, the findings suggest medications that boost the effect of natural brain opioids might be a better way to reduce anxiety than 'receptor-binding' opioid drugs like morphine, which have major side effects. Fear and anxiety help defend us against harm, and are largely controlled via neural circuits of interconnected nerve cells and synaptic activity in the brain's amygdala that allow neurons to pass electrical or chemical signals to each other. Specialised neural circuits control these emotions, but disturbances in the circuits can cause prolonged and disabling emotional responses that are out of proportion to threatening events..."Our findings show that opioids produced and released by our own brain cells strongly regulate these critical neural circuits that are important for fear responses. "We also show that we could boost the actions of these endogenous opioids using a novel pharmacological approach."
https://medicalxpress.com/news/2017-03-boosting-natural-brain-opioids-anxiety.html#jCp
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